BAGUS SUPRIYANTO, - (2021) STUDI MONITORING EFEK SAMPING OBAT ANTITUBERKULOSIS FDC KATEGORI 1 DI SALAH SATU RUMAH SAKIT SWASTA DI KOTA BANDUNG. Skripsi thesis, Sekolah Tinggi Farmasi Indonesia.
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Abstract
WHO 2017 mengungkapkan angka insiden tuberkulosis di Indonesia sebesar 391 per 100.000 penduduk dan angka kematian 42 per 100.000 penduduk. Di Indonesia pada tahun 2017 ditemukan jumlah kasus TB paru sebanyak 425.089 kasus, meningkat bila dibandingkan semua kasus TB paru yang ditemukan pada tahun 2016 sebesar 360.565 kasus. Efek samping merupakan salah satu faktor yang mempengaruhi putusnya terapi pada penderita tuberkulosis. Kejadian resistensi obat merupakan potensi besar kejadian yang mungkin terjadi. Penelitian ini bertujuan untuk mendapatkan data efek samping penggunaan obat antituberkulosis kombinasi dosis tetap, obat-obatan pereda efek samping yang terjadi dan keterkaitan pencitraan laboratorium yang harus dilakukan. Penelitian ini menggunakan tipe time series yang dilakukan terhadap pasien baru penderita tuberkulosis di salah satu rumah sakit swasta di Kota Bandung pada bulan Januari 2021. Pasien diikuti selama 6 bulan pengobatan hingga periode penelitian berakhir. Pasien diwawancara mengenai efek samping obat yang dialami setiap bulannya saat mengambil obat. Selain itu, data diambil dari status pasien ketika kontrol bersama dokter. Jumlah sampel dalam penelitian ini adalah 13 pasien, semuanya masih patuh dalam menjalani terapi. Frekuensi kejadian efek samping yang paling sering timbul selama 6 bulan pengobatan adalah nyeri sendi. Efek samping lain yang sering timbul akibat penggunaan OAT yaitu: mual,gatal, gangguan lambung dan gangguan lainnya seperti: kesemutan, pusing, demam, bengkak dan nyeri kaki. Berdasarkan hasil penelitian dapat disimpulkan bahwa dengan adanya efek samping yang terjadi tidak menyebabkan menurunnya keinginan pasien untuk meminum obat. Hal ini dapat terjadi karena adanya komunikasi yang baik antara pasien dengan petugas mengenai proses pengobatan tuberkulosis. Disarankan agar pemantauan efek samping diikuti dengan pengecekan laboratorium secara rutin dan peninjauan kembali terkait komorbid atau penyakit penyerta pasien. ---- WHO 2017 revealed that the incidence of tuberculosis in Indonesia was 391 per 100,000 population and the death rate was 42 per 100,000 population. In Indonesia in 2017, the number of pulmonary TB cases was 425,089 cases, an increase when compared to all cases of pulmonary TB found in 2016 of 360,565 cases. Side effects are one of the factors that influence the discontinuation of therapy in tuberculosis patients. The incidence of drug resistance is a large potential event that may occur. This study aims to obtain data on side effects of using fixed-dose combination antituberculosis drugs, drugs that relieve side effects that occur and the relevance of laboratory imaging that must be carried out. This study uses a time series type which was conducted on new patients with tuberculosis at a private hospital in Bandung City in January 2021. Patients were followed for 6 months of treatment until the study period ended. Patients were interviewed about the side effects of drugs they experienced every month while taking the drugs. In addition, data were taken from the patient's status when the control was with the doctor. The number of samples in this study were 13 patients, all of whom were still compliant in undergoing therapy. The frequency of the occurrence of side effects that most often occurred during the 6 months of treatment was joint pain. Other side effects that often arise due to the use of OAT are: nausea, itching, stomach disorders and other disorders such as: tingling. dizziness, fever, swelling and leg pain. Based on the results of the study, it can be concluded that the presence of side effects that occur does not cause a decrease in the patient's desire to take the drug. This can happen because of good communication between patients and staff regarding the tuberculosis treatment process. It is recommended that monitoring of side effects be followed by routine laboratory checks and a review of the patient's comorbidities or comorbidities
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | Efek Samping, Tuberkolosis Paru, Antituberkulosis |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RM Therapeutics. Pharmacology |
| Divisions: | Program Studi S1 Farmasi |
| Depositing User: | pustakawan - - |
| Date Deposited: | 14 Aug 2024 02:49 |
| Last Modified: | 14 Aug 2024 02:49 |
| URI: | http://repository.stfi.ac.id/id/eprint/811 |
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