SANI NURLAELA FITRIANSYAH, - and RIKA HARTATI, - and IRDA FIDRIANNY, - (2022) Effect of Different Solvent on Phytochemical Content, Tyrosinase Inhibition and Antioxidant Activities of Campolay (Pouteria campechiana kunth. [Baehni.]). Open Access Macedonian Journal of Medical Sciences (OAMJMS), 10 (A). pp. 158-163. ISSN 1857-9655
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Abstract
BACKGROUND: Pouteria campechiana leaves are reported to have phenol and flavonoid compounds. Phenolic and flavonoid compounds can act as tyrosinase inhibitor and antioxidant. AIM: The purpose of this study was to compare phytochemical content, tyrosinase inhibition, antioxidant activities, and determine of marker compound from P. campechiana leaves extract with different polarities solvent. METHODS: In addition, the content of marker compound from P. campechaina leaves extract was determined by HPLC. RESULTS: The highest total phenolic content (TPC) 7.83 GAE/100 g extract, IC50 of tyrosinase 171.512 ± 1.352 and IC50 of DPPH 0.968 ± 0.008 was given by ethanolic extract (DE). Meanwhile ethyl acetate extract (DEA) had the highest of total flavonoid content 2.544 ± 0.554 QEA/100 g extract. The TPC correlated with tyrosinase inhibitory activity and antioxidant activity. CONCLUSION: Quercitrin was as marker compound from P. campechiana leaves extract, and quercitrin content in the DEA of P. campechiana leaves was 3.539%, while in the DE was 0.153%.
Item Type: | Article |
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Uncontrolled Keywords: | Pouteria campechiana, Tyrosinase, Antioxidant, Quercitrin |
Subjects: | Q Science > Q Science (General) R Medicine > RM Therapeutics. Pharmacology |
Divisions: | Lembaga Penelitian dan Pengabdian Masyarakat > Publikasi Penelitian |
Depositing User: | - Sani Nurlaela Fitriansyah - |
Date Deposited: | 26 Jul 2024 04:04 |
Last Modified: | 09 Aug 2024 03:48 |
URI: | http://repository.stfi.ac.id/id/eprint/740 |
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