SABELA TRI VANI, - (2025) PENETAPAN KADAR FENOLIK, FLAVONOID, SUN PROTECTION FACTOR (SPF) DARI EKSTRAK ETANOL DAUN SINGAWALANG (Petiveria alliacea L.) MENGGUNAKAN SPEKTROFOTOMETRI UV – VIS. Skripsi thesis, Sekolah Tinggi Farmasi Indonesia.
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Abstract
Daun singawalang (Petiveria alliacea L.) merupakan tanaman obat tradisional yang mengandung senyawa metabolit sekunder seperti fenolik dan flavonoid. Kedua senyawa ini diketahui memiliki aktivitas antioksidan dan berpotensi memberikan perlindungan terhadap kerusakan kulit akibat paparan sinar ultraviolet (UV). Penelitian ini bertujuan untuk menentukan kadar fenolik total, kadar flavonoid total, serta nilai Sun Protection Factor (SPF) dari ekstrak etanol daun singawalang. Ekstraksi dilakukan dengan metode maserasi menggunakan pelarut etanol 70%. Penetapan kadar fenolik menggunakan metode Folin – Ciocalteu, sedangkan kadar flavonoid ditetapkan dengan metode kompleksasi AlCl₃. Penentuan nilai SPF dilakukan secara in vitro menggunakan spektrofotometri UV – Vis pada panjang gelombang 290–320 nm. Hasil analisis menunjukkan bahwa ekstrak memiliki kadar fenolik sebesar 4,213 mg GAE/g dan kadar flavonoid sebesar 2,211 mg QE/g. Nilai SPF dari ekstrak berkisar antara 2,1 (proteksi minimal) hingga 7,8 (proteksi ekstra), tergantung pada konsentrasi ekstrak. Berdasarkan hasil tersebut, dapat disimpulkan bahwa ekstrak etanol daun singawalang memiliki kandungan senyawa aktif yang mendukung potensinya sebagai agen pelindung kulit terhadap paparan sinar UV. ------ Singawalang leaf (Petiveria alliacea L.) is a traditional medicinal plant that contains secondary metabolite compounds such as phenolics and flavonoids. These compounds are known to possess antioxidant activity and have the potential to provide protection against skin damage caused by ultraviolet (UV) radiation. This study aims to determine the total phenolic content, total flavonoid content, and Sun Protection Factor (SPF) value of the ethanol extract of singawalang leaves. Extraction was performed using the maceration method with 70% ethanol as the solvent. The determination of phenolic content was conducted using the FolinCiocalteu method, while the flavonoid content was determined using the AlCl₃ complexation method. The SPF value was assessed in vitro using UV-Vis spectrophotometry at wavelengths of 290–320 nm. The analysis results showed that the extract had a phenolic content of 4.213 mg GAE/g and a flavonoid content of 2.211 mg QE/g. The SPF value of the extract ranged from 2.1 (minimal protection) to 7.8 (extra protection), depending on the concentration of the extract. Based on these results, it can be concluded that the ethanol extract of singawalang leaves contains active compounds that support its potential as a skin protective agent against UV radiation exposure.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | Daun Singawalang, fenolik, flavonoid, SPF. ----- Singawalang leaf, phenolic, flavonoid, SPF |
| Subjects: | Q Science > QH Natural history > QH301 Biology R Medicine > R Medicine (General) |
| Divisions: | Program Studi S1 Farmasi |
| Depositing User: | pustakawan - - |
| Date Deposited: | 09 Sep 2025 02:17 |
| Last Modified: | 09 Sep 2025 02:17 |
| URI: | http://repository.stfi.ac.id/id/eprint/2774 |
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