JENISTA BUDIMAN, - (2020) UJI AKTIVITAS ANTIBAKTERI PADA SEDIAAN PERMEN GUMMY KOMBINASI EKSTRAK JAHE MERAH, SEREH DAPUR DAN KAYU MANIS TERHADAP BAKTERI STREPTOCOCCUS MUTANS. Skripsi thesis, Sekolah Tinggi Farmasi Indonesia.
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Abstract
Karies gigi dapat disebabkan oleh asam yang terdapat pada karbohidrat melalui perantara mikroorganisme yang ada dalam saliva, yaitu Streptococcus mutans. Tanaman yang berpotensi menghambat pertumbuhan bakteri Streptococcus mutans adalah jahe merah, sereh dapur dan kayu manis. Tujuan penelitian ini adalah untuk mengetahui aktivitas antibakteri Streptococcus mutans dalam permen gummy dengan kombinasi ekstrak jahe merah, sereh dapur dan kayu manis. Metode difusi agar digunakan untuk mengetahui aktivitas antibakteri ekstrak dan permen gummy. Evaluasi permen gummy yang dilakukan meliputi organoleptis, keseragaman bobot, kadar air, elasatisitas, pH dan tingkat kesukaan. Hasil penelitian menunjukkan bahwa ekstrak jahe merah, ekstrak sereh dapur, ekstrak kayu manis memiliki aktivitas antibakteri terhadap Streptococcus mutans. Formulasi 3 permen gummy mampu menghambat Streptococcus mutans dengan diameter zona bening 7,65 mm. Dengan demikian disimpulkan bahwa permen gummy stabil dalam penyimpanan dan dalam satu permen gummy terdapat zona bening 7,65 mm terhadap bakteri Streptococcus mutans. --- Dental caries of teeth might caused by acids that exist in carbohydrates through the intermediaries of microorganisms that exist in saliva, which is Streptococcus mutans. Plants that have the potential to inhibit the bacterial growth of Streptococcus mutants are red ginger, lemongrass and cinnamon. The purpose of this study is to determined the antibacterial activity of Streptococcus mutants in gummy candy with combinations of red ginger extract, lemongrass, and cinnamon. The agar diffusion method was used to antibacterial activities of extracts and gummy candy. The evaluation of gummy candy includes physical stability, weight uniformity, moisture content, elasatisity, pH. The results showed that red ginger extract, lemongrass extract, cinnamon extract have the antibacterial activity against Streptococcus mutans. The third formulation of gummy candy could inhibits Streptococcus mutans with diameter zone inhibition 7.65 mm. Thus, conclude that the gummy candy was stable in strorage and in one gummy candy could inhibit Streptococcus mutans with diameter zone inhibition 7,65 mm .
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | Jahe Merah, Sereh Dapur, Kayu Manis, Streptococcus mutans, Permen Gummy --- Red Ginger, Lemongrass, Cinnamon, Streptococcus mutants, Gummy Candy |
| Subjects: | Q Science > Q Science (General) R Medicine > R Medicine (General) |
| Divisions: | Program Studi S1 Farmasi |
| Depositing User: | pustakawan - - |
| Date Deposited: | 03 Oct 2024 03:59 |
| Last Modified: | 03 Oct 2024 03:59 |
| URI: | http://repository.stfi.ac.id/id/eprint/1309 |
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