NURLASTRI, - (2021) OPTIMASI BASIS MASKER GEL PEEL-OFF DAN UJI AKTIVITAS ANTIBAKTERI DARI EKSTRAK BIJI KOΡΙ ARABIKA (Coffea arabica L.) DEFECT. Skripsi thesis, Sekolah Tinggi Farmasi Indonesia.
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Abstract
Kopi arabika defect biji kopi yang secara fisik sudah tidak utuh atau tidak lulus quality control. Biji kopi defect memiliki senyawa yang memiliki aktivitas sebagai antibakteri sehingga dapat dipertimbangkan untuk dimanfaatkan salah satunya menjadi produk kosmetik. Tujuan penelitian ini yaitu untuk menguji aktivitas antibakteri ekstrak biji kopi arabika defect terhadap bakteri Staphylococcus epidermidis dan memformulasikan basis masker gel peel-off yang merupakan salah satu produk yang memiliki aktivitas antibakteri. Masker gel peel-off dengan basis PVA, bahan gelling agent, humektan, in, pengawet dan pembawa. Metode ekstraksi biji kopi arabika defect yang digunakan yaitu maserasi dengan pelarut etanol 96% selama 3x24 jam. Dan konsentrasi ekstrak yang digunakan untuk menentukan konsentrasi hambat minimum yaitu minimum yaitu 50%, 35%, 20%, dan 5% serta diikuti dengan konsentrasi 4%, 3%, 2%, dan 1%. Pada pengujian untuk menentukan konsentrasi hambat minimum hasil penelitian yang diperoleh menunjukkan bahwa (KHM) ekstrak biji kopi arabika defect dengan konsentrasi 2% menghasilkan daya hambat 2,03±1,43 mm dengan kategori lemah. Formulasi dasar menggunakan tiga variasi konsentrasi gelling agent HPMC berturut-turut yaitu 2%, 2,5%, dan 5%. Ketiga basis tidak mengalami perubahan organoleptis, homogenitas yang baik, terjadi peningkatan viskositas, terjadinya penurunan daya sebar, tidak terjadinya sineresis dan terjadinya penurunan pli. Secara keseluruhan. basis masker gel peel-off stabil selama penyimpanan. --- Arabica coffee is a coffee bean that is physically not intact or does not pass quality control. Defect coffee beans have compounds that have antibacterial activity so that they can be considered to be used as cosmetic products. The purpose of this study was to test the antibacterial activity of defect arabica coffee bean extract against Staphylococcus epidermidis bacteria and to formulate a peel-off gel mask bate which is one of the products that has antibacterial activity. Peel-off gel mask with PVA base, gelling agent, humectant, preservative and carrier. The extraction method of Arabica defect coffee beans used wat maceration with 96% ethanol solvent for 3x24 hours. And the concentration of extract used to determine the minimum inhibitory concentration was 30%, 35%. 20%, and 5% and followed by concentrations of 4%, 3%, 25%, and 15%. In the text to determine the minimum inhibitory concentration, the results obtained showed that (MIC) defective Arabica coffee bean extract with a concentration of 2% produced an inhibitory power of 2.034:1.43 mm in the weak category. The basic formulation uses three variations of HPMC gelling agent concentration, respectively, namely 25%, 2.5%, and 5%. The three bases did not experience organoleptic changes, good homogeneity, an increase in viscosity, a decrease in dispersion, no syneresis and a decrease in pH. Overall the peel-off gel mask base is stable during storage.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | Biji kopi arabika defect, masker gel peel-off, antibakteri, Staphylococcus epidermidis, dan gelling agent --- Arabica coffee defect, peel-off gel mask, antibacterial, Staphylocoссия epidermidis, ond gelling agent. |
| Subjects: | Q Science > Q Science (General) R Medicine > R Medicine (General) |
| Divisions: | Program Studi S1 Farmasi |
| Depositing User: | pustakawan - - |
| Date Deposited: | 07 Sep 2024 01:43 |
| Last Modified: | 07 Sep 2024 01:43 |
| URI: | http://repository.stfi.ac.id/id/eprint/1158 |
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