REVIEW: AKTIVITAS ANTIINFLAMASI dan ANALGETIK DARI GENUS Ficus

NUR ENDAH DIANTINI, - (2021) REVIEW: AKTIVITAS ANTIINFLAMASI dan ANALGETIK DARI GENUS Ficus. Skripsi thesis, Sekolah Tinggi Farmasi Indonesia.

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Abstract

Inflamasi merupakan respon protektif lokal yang disebabkan oleh kerusakan jaringan akibat trauma fisik, kimiawi atau biologi. Ficus termasuk ke dalam famili moraceae, terdapat sekitar 500 spesies yang tersebar luas dinegara tropis dan subtropis. Genus Ficus memiliki aktivitas sebagai antiinflamasi dan analgetik dengan bagian tanaman daun, buah dan kulit. Review ini bertujuan untuk mengumpulkan data ilmiah mengenai kandungan metabolit sekunder yang terdapat pada beberapa spesies genus serta melihat potensi antiinflamasi dan analgetik pada genus Ficus. Dari hasil review genus Fleus sebagian besar memiliki metabolit sekunder yaitu flavonoid, steroid dan terpenoid metabolit ini berperan dalam aktivitas antiinflamasi dan analgetik. Metode antiinflamasi yang paling banyak digunakan yaitu metode pembentukan edema sedangkan untuk pengujian analgetik metode yang paling banyak digunakan yaitu writhing test. Ekstrak metanol daan Ficus microcarpa memiliki aktivitas antiinflamasi dan analgetik paling potensial diantara semus spesies dari genus Ficus. Memiliki nilai persen inhibisi pada uji antiinflamasi adalah 96,8% dan uji analgetik sebesar 100% --- Inflammation is a local protective response caused by tissue damage due to physical, chemical, or biological trauma. Ficus belongs to the family Moraceae, there are about 500 species that are widespread in tropical and subtropical countries. The genus Ficus has activities as anti-inflammatory and analgetic with plant parts of leaves, fruit, and skin. The review aims to collect scientific data on the content of secondary metabolites found in several species of the genus and look at the anti-inflammatory and analgesic potential of the genus Ficus. From the results of the review of the gemis, Ficus mostly have secondary metabolites namely flavonoids, steroids and terpenoid metabolites play a role in anti- inflammatory and analgesic activity. The most widely used anti-inflammatory method is the edema formation method while for analgetic testing the most widely used method is the writhing test, Methanol extract of Ficus microcarpa leaves has the most potent anti-inflammatory and analgetic activity among all species of the genus Ficus. Having an inhibition percent value on anti-inflammatory tests is 96.8% and analgetic tests by 100%

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	analgetik, antiinflamasi, genus Ficus, persen inhibisi. --- analgesic, anti-inflammatory, Ficus, percent inhibition.
Subjects:	Q Science > Q Science (General) R Medicine > R Medicine (General)
Divisions:	Program Studi S1 Farmasi
Depositing User:	pustakawan - -
Date Deposited:	07 Sep 2024 01:55
Last Modified:	07 Sep 2024 01:55
URI:	http://repository.stfi.ac.id/id/eprint/1114

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