MITA RISKA, - (2024) ANALISIS EFEKTIVITAS BIAYA PENGGUNAAN REGIMEN STR DENGAN REGIMEN BPaL PADA PASIEN MULTIDRUG RESISTANT TUBERCULOSIS DI RSUP Dr. HASAN SADIKIN BANDUNG. Skripsi thesis, Sekolah Tinggi Farmasi Indonesia.
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Abstract
Multidrug Resistant Tuberculosis (MDR-TB) adalah penyakit tuberkulosis yang resisten terhadap isoniazid, rifampisin dan obat lini pertama. Studi farmakoekonomi diperlukan dalam menganalisis pemilihan regimen pengobatan dengan mempertimbangkan dari segi biaya dan efektivitas. Penelitian ini bertujuan untuk mengetahui manakah nilai cost effectivness antara regimen STR (short time regiment) dan regimen BPaL (Bedaquiline, Pretomanid, Linezolid) pada pengobatan MDR-TB di RSUP Dr. Hasan Sadikin Bandung serta mengetahui regimen yang paling mempengaruhi nilai cost effectiveness. Pada penelitian ini pengumpulan data dilakukan secara retrospektif dari rekam medis pasien dan Sistem Informasi Tuberkulosis (SITB) periode Januari 2022- Februari 2024. Data biaya yang digunakan meliputi total biaya medik dari rumah sakit/healthcare perspective (biaya obat, biaya pemeriksaan EKG, biaya pengambilan darah/lab dan biaya rontgen). Nilai efektivitas dalam penelitian ini diukur dari konversi kultur sputum. Hasil menunjukkan nilai Average Costeffectiveness Ratio (ACER) pada regimen BPaL yaitu sebesar Rp170.409,89 nilai tersebut lebih rendah dibandingkan dengan regimen STR yaitu sebesar Rp180.902,58 sehingga regemen BPaL lebih cost-effectivness dibandingkan regimen STR. Hasil uji sensitivitas dari nilai ACER menunjukkan regimen STR memiliki rentang yang paling panjang sehingga regimen STR lebih mempengaruhi nilai cost-effectivness. ---- Multidrug Resistant Tuberculosis (MDR-TB) is a tuberculosis disease that is resistant to isoniazid, rifampicin and first-line drugs. Pharmacoeconomic studies are needed to analyze the choice of treatment regimen by considering cost and effectiveness. This study aims to determine the cost-effectiveness value between the STR regimen (short time regiment) and the BPaL regimen (Bedaquiline, Pretomanid, Linezolid) in the treatment of MDR-TB at RSUP Dr. Hasan Sadikin Bandung and knowing the regimen that most influences the cost-effectiveness value. In this study, data collection was carried out retrospectively from patient medical records and the Tuberculosis Information System (SITB) for the period January 2022-February 2024. The cost data used includes total medical costs from a hospital/healthcare perspective (drug costs, ECG examination costs, collection costs blood/lab and x-ray costs). The effectiveness value in this study was measured from sputum culture conversion. The results show that the Average Cost-effectiveness Ratio (ACER) value for the BPaL regimen is IDR 170,409.89, this value is lower than the STR regimen, namely IDR 180,902.58, so the BPaL regimen is more cost-effective than the STR regimen. The sensitivity test results of the ACER value show that the STR regimen has the longest range so that the STR regimen influential the cost-effectiveness value more.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | ACER, analisis efektivitas biaya, MDR-TB. ---- ACER, cost effectiveness analysis, MDR-TB |
| Subjects: | R Medicine > R Medicine (General) R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
| Divisions: | Program Studi S1 Farmasi |
| Depositing User: | pustakawan - - |
| Date Deposited: | 19 Aug 2024 08:15 |
| Last Modified: | 19 Aug 2024 08:15 |
| URI: | http://repository.stfi.ac.id/id/eprint/965 |
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