MONITORING KESESUAIAN REGIMEN OBAT PADA PASIEN KANKER PAYUDARA DI RSUD WELAS ASIH KABUPATEN BANDUNG TAHUN 2024

NANDA SARI, - (2025) MONITORING KESESUAIAN REGIMEN OBAT PADA PASIEN KANKER PAYUDARA DI RSUD WELAS ASIH KABUPATEN BANDUNG TAHUN 2024. Skripsi thesis, Sekolah Tinggi Farmasi Indonesia.

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Abstract

Kanker payudara merupakan jenis kanker dengan angka kejadian tertinggi pada wanita di Indonesia. Kemoterapi menjadi terapi utama yang harus disesuaikan dengan Pedoman Nasional Pelayanan Kedokteran (PNPK) Kanker Payudara 2018 agar terapi efektif dan aman. Penelitian ini bertujuan mengetahui karakteristik pasien, jenis regimen kemoterapi yang digunakan, serta kesesuaian dosis obat pada pasien kanker payudara di RSUD Welas Asih Kabupaten Bandung tahun 2024. Penelitian ini bersifat deskriptif evaluatif dengan pendekatan retrospektif terhadap 66 data rekam medis pasien kanker payudara periode Januari-Desember 2024. Hasil penelitian menunjukkan bahwa pasien terbanyak berusia 46–65 tahun sebanyak 33 pasien (50%) dan stadium IIIA-IIIB sebanyak 48 pasien (72,73%). Regimen yang paling banyak digunakan adalah TC (Docetaxel + Cyclophosphamide) sebanyak 39 pasien (59,09%), seluruhnya (100%) telah sesuai dengan PNPK 2018 baik dari segi obat maupun dosis. Sementara itu, regimen AC (Doxorubicin + Cyclophosphamide) digunakan pada 27 pasien (40,91%) seluruhnya mengalami dosis kurang dibandingkan standar PNPK. Penurunan dosis dilakukan sebagai bentuk penyesuaian untuk mengurangi risiko kardiotoksisitas dan menyesuaikan dengan kondisi klinis pasien. ------- Breast cancer is the most common type of cancer among women in Indonesia. Chemotherapy is the primary treatment that must be adjusted to the 2018 National Guidelines for Medical Services (PNPK) for Breast Cancer to ensure effective and safe treatment. This study aims to determine the characteristics of patients, the types of chemotherapy regimens used, and the appropriateness of drug doses in breast cancer patients at Welas Asih Regional General Hospital, Bandung Regency, in 2024. This study is descriptive evaluative with a retrospective approach to 66 medical records of breast cancer patients from January to December 2024. The results showed that the majority of patients were aged 46–65 years (33 patients, 50%) and had stage IIIA-IIIB disease (48 patients, 72.73%). The most commonly used regimen was TC (Docetaxel + Cyclophosphamide) in 39 patients (59.09%), all of whom (100%) were in accordance with the 2018 PNPK in terms of both drugs and dosage. Meanwhile, the AC regimen (Doxorubicin + Cyclophosphamide) was used in 27 patients (40.91%), all of whom received lower doses than the PNPK standard. The dose reduction was done as an adjustment to reduce the risk of cardiotoxicity and to adjust to the patient's clinical condition.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	kanker payudara, kemoterapi, regimen TC, regimen AC, PNPK 2018. ----- breast cancer, chemotherapy, TC regimen, AC regimen, PNPK 2018.
Subjects:	R Medicine > R Medicine (General) R Medicine > RA Public aspects of medicine
Divisions:	Program Studi S1 Farmasi
Depositing User:	pustakawan - -
Date Deposited:	20 Nov 2025 06:58
Last Modified:	20 Nov 2025 06:58
URI:	http://repository.stfi.ac.id/id/eprint/3543

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