ISOLASI DAN KARAKTERISASI SENYAWA FLAVONOID DARI DAUN BENALU MANGGA (Dendrophthoe pentandra (L.) Miq.)

UMIRA DESIFA, - (2025) ISOLASI DAN KARAKTERISASI SENYAWA FLAVONOID DARI DAUN BENALU MANGGA (Dendrophthoe pentandra (L.) Miq.). Skripsi thesis, Sekolah Tinggi Farmasi Indonesia.

	Text S_PSSF_A242027_Title.pdf Download (768kB)
	Text S_PSSF_A242027_Chapter1.pdf Restricted to Repository staff only Download (266kB)
	Text S_PSSF_A242027_Chapter2.pdf Restricted to Repository staff only Download (389kB)
	Text S_PSSF_A242027_Chapter3.pdf Restricted to Repository staff only Download (289kB)
	Text S_PSSF_A242027_Chapter4.pdf Restricted to Repository staff only Download (512kB)
	Text S_PSSF_A242027_Chapter5.pdf Restricted to Repository staff only Download (258kB)
	Text S_PSSF_A242027_Appendix.pdf Restricted to Repository staff only Download (1MB)

Abstract

Benalu merupakan tumbuhan parasit yang menempel pada batang atau cabang pohon inang, salah satunya pohon mangga (Mangifera indica L.). Daun benalu mangga (Dendrophthoe pentandra (L.) Miq.) diketahui mengandung senyawa metabolit golongan flavonoid. Penelitian terdahulu berhasil mengisolasi flavonoid menggunakan pelarut metanol yang bersifat polar, namun menghasilkan banyak senyawa pengotor. Untuk mengurangi senyawa pengotor tersebut, pada penelitian ini digunakan etil asetat yang bersifat semipolar sebagai pelarut. Proses isolasi dilakukan dengan metode maserasi menggunakan pelarut etil asetat. Ekstrak kental yang diperoleh dipisahkan dengan etanol kemudian dilanjutkan dengan pelarut n-heksana secara bertahap. Hasil Penelitian menunjukan rendemen isolat sebesar 1,06% dan uji skrining flavonoid memberikan hasil positif yang ditandai dengan perubahan warna menjadi merah. Analisis spektrofotometri UV menunjukkan dua puncak serapan pada panjang gelombang 256 nm dan 351 nm, sedangkan hasil FTIR menunjukan bahwa adanya gugus fungsi –OH, C=O, C=C, dan C–O dan uji titik leleh diperoleh pada suhu 178–180 ̊C. ------- Mistletoe is a parasitic plant that attaches to the branches or stems of host trees, one of which is the mango tree (Mangifera indica L.). The leaves of mango mistletoe (Dendrophthoe pentandra (L.) Miq.) are known to contain secondary metabolite compounds of the flavonoid group. Previous studies successfully isolated flavonoids using methanol as a polar solvent; however, this method produced many impurities. To reduce these impurities, ethyl acetate, a semipolar solvent, was used as an alternative in this study. The isolation process was carried out by maceration using ethyl acetate as the solvent. The resulting thick extract was further separated using ethanol and washed with n-hexane sequentially. The results showed an isolate yield of 1.06%, and flavonoid screening produced a positive result indicated by a red color change. UV spectrophotometric analysis showed two absorption peaks at wavelengths of 256 nm and 351 nm, while FTIR analysis indicated the presence of functional groups –OH, C=O, C=C, and C–O. The melting point test showed that the isolate changed from solid to liquid at a temperature range of 178–180 °C.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Benalu Mangga, Flavonoid, Isolasi, spektrofotometri UV, FTIR. ------- Mango mistletoe, flavonoid, isolation, UV spectrophotometry, FTIR
Subjects:	Q Science > Q Science (General) Q Science > QD Chemistry
Divisions:	Program Studi S1 Farmasi
Depositing User:	pustakawan - -
Date Deposited:	20 Nov 2025 06:39
Last Modified:	20 Nov 2025 06:39
URI:	http://repository.stfi.ac.id/id/eprint/3540

Actions (login required)

View Item