HUBUNGAN REGIMEN TERAPI DENGAN STADIUM PADAPASIEN KANKER SERVIKS DI RAWAT JALAN RSUD WELAS ASIH JAWA BARAT

DENIS APRILLIONA ROMANTISA, - (2025) HUBUNGAN REGIMEN TERAPI DENGAN STADIUM PADAPASIEN KANKER SERVIKS DI RAWAT JALAN RSUD WELAS ASIH JAWA BARAT. Skripsi thesis, Sekolah Tinggi Farmasi Indonesia.

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Abstract

Kanker serviks merupakan salah satu penyebab utama kematian pada perempuandi Indonesia. Penelitian ini bertujuan untuk mengetahui hubungan antara regimenterapi dengan stadium kanker serviks pada pasien rawat jalan di RSUD WelasAsih Jawa Barat. Desain penelitian yang digunakan adalah deskriptif kuantitatifdengan pendekatan retrospektif, menggunakan data rekam medis pasien kanker serviks periode Januari-Desember 2024. Data yang dianalisis meliputi karakteristik pasien, jenis obat kemoterapi, ketepatan dosis, dan hubungan antararegimen terapi dengan stadium penyakit. Hasil penelitian menunjukkan bahwasebagian besar pasien berada pada kelompok usia 46 55 tahun (38,6%) danstadium III (27,7%). Regimen terapi terbanyak adalah cisplatin tunggal (90,1%) dengan ketepatan dosis sebesar 75,2% sesuai Pedoman Pelayanan Klinis 2015. Uji Chi-Square menunjukkan adanya hubungan signifikan antara regimen terapi danstadium penyakit (p=0,002), di mana pasien stadium lanjut lebih sering menerimakombinasi carboplatin+paclitaxel. Hasil ini menunjukkan penerapan terapi individualisasi sesuai kondisi klinis pasien. Penelitian ini diharapkan menjadi dasar peningkatan pelayanan farmasi klinik dan rasionalisasi penggunaan obat kemoterapi pada pasien kanker serviks. ------- Cervical cancer is one of the leading causes of death among women in Indonesia. This study aimed to determine the relationship between chemotherapy regimensand cancer stage among outpatient cervical cancer patients at Welas AsihHospital, West Java. This research used a descriptive quantitative design with aretrospective approach based on medical record data from January-December2024. The analyzed variables included patient characteristics, chemotherapytypes, dose accuracy, and the relationship between treatment regimens andcancer stages. Results showed that most patients were aged 46 55 years (38.6%)and in stage III (27.7%). The most common regimen was single-agent cisplatin(90.1%) with 75.2% dose accuracy according to 2015 clinical guidelines. TheChi-Square test revealed a significant relationship between chemotherapyregimens and cancer stage (p=0.002), where advanced-stage patients oftenreceived carboplatin+paclitaxel combinations. These findings indicate theimplementation of individualized therapy based on clinical conditions. This studyprovides insights for optimizing clinical pharmacy services and rationalizingchemotherapy use in cervical cancer management.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	kanker serviks, regimen kemoterapi, cisplatin, stadium penyakit, evaluasi terapi. ------ cervical cancer, chemotherapy regimen, cisplatin, disease stage, therapy evaluation
Subjects:	R Medicine > R Medicine (General) R Medicine > RM Therapeutics. Pharmacology
Divisions:	Program Studi S1 Farmasi
Depositing User:	pustakawan - -
Date Deposited:	20 Nov 2025 03:10
Last Modified:	20 Nov 2025 03:10
URI:	http://repository.stfi.ac.id/id/eprint/3521

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