ROZA DANIA RIZKY, - (2025) UJI AKTIVITAS ANTIOKSIDAN AMPAS DARI HASIL PROSES EKSTRAKSI KUNYIT (Curcuma domestica Val.) MENGGUNAKAN METODE Ferric Reducing Antioxidant Power (FRAP). Skripsi thesis, Sekolah Tinggi Farmasi Indonesia.
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Abstract
Antioksidan berperan penting dalam melindungi tubuh dari kerusakan akibat radikal bebas. Salah satu sumber antioksidan alami adalah kunyit (Curcuma domestica Val.) yang diketahui kaya akan senyawa kurkuminoid. Selama proses ekstraksi, ampas kunyit umumnya hanya menjadi limbah, walaupun masih berpotensi mengandung senyawa bioaktif. Penelitian ini bertujuan untuk menilai aktivitas antioksidan ampas ekstrak kunyit menggunakan metode Ferric Reducing Antioxidant Power (FRAP). Sampel ampas diperoleh dari Sekolah Tinggi Farmasi Indonesia dan diuji kandungan metabolit sekunder. Hasil skrining fitokimia menunjukkan adanya flavonoid, alkaloid, dan triterpenoid. Aktivitas antioksidan ditentukan dengan reagen FRAP pada panjang gelombang 594 nm. Hasil penelitian menunjukkan nilai FRAP ampas ekstrak kunyit sebesar 37,230 µmol Fe²⁺/g, sedangkan vitamin C sebagai kontrol positif sebesar 30,470 µmol Fe²⁺/g. Nilai IC₅₀ ampas ekstrak kunyit dan vitamin C termasuk kategori sangat kuat (<50). Oleh karena itu, ampas ekstrak kunyit berpotensi dikembangkan sebagai sumber antioksidan alami dan memiliki nilai tambah untuk dimanfaatkan secara berkelanjutan. ------ Antioxidants are essential in protecting the body from damage caused by free radicals. One natural source of antioxidants is turmeric (Curcuma domestica Val.), which is known to be rich in curcuminoid compounds. During the extraction process, turmeric residue is generally discarded as waste, although it still has the potential to contain bioactive compounds. This study aimed to evaluate the antioxidant activity of turmeric extract residue using the Ferric Reducing Antioxidant Power (FRAP) method. Residue samples were obtained from Sekolah Tinggi Farmasi Indonesia and tested for their secondary metabolite content. Phytochemical screening revealed the presence of flavonoids, alkaloids, and triterpenoids. Antioxidant activity was determined using the FRAP reagent at a wavelength of 594 nm. The results showed that the FRAP value of turmeric extract residue was 37.230 µmol Fe²⁺/g, while vitamin C as a positive control was 30.470 µmol Fe²⁺/g. The IC₅₀ values of turmeric extract residue and vitamin C were both classified as very strong (<50). Therefore, turmeric extract residue has the potential to be developed as a natural antioxidant source and provides added value for sustainable utilization.
| Item Type: | Thesis (Skripsi) |
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| Uncontrolled Keywords: | antioksidan, kunyit, ampas ekstrak, FRAP, IC50. ----- antioxidants, turmeric, extract residue, FRAP, IC₅₀ |
| Subjects: | Q Science > Q Science (General) R Medicine > RM Therapeutics. Pharmacology |
| Divisions: | Program Studi S1 Farmasi |
| Depositing User: | pustakawan - - |
| Date Deposited: | 19 Nov 2025 02:56 |
| Last Modified: | 19 Nov 2025 02:56 |
| URI: | http://repository.stfi.ac.id/id/eprint/3489 |
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