GAMBARAN EFEK PENGGUNAAN KAPSUL BRAZ 131 SEBAGAI ADJUVANT PADA PENYANDANG TALASEMIA

SURISTA NOVIA, - (2025) GAMBARAN EFEK PENGGUNAAN KAPSUL BRAZ 131 SEBAGAI ADJUVANT PADA PENYANDANG TALASEMIA. Skripsi thesis, Sekolah Tinggi Farmasi Indonesia.

	Text S_PSSF_A233029_Title.pdf Download (537kB)
	Text S_PSSF_A233029_Chapter1.pdf Restricted to Repository staff only Download (204kB)
	Text S_PSSF_A233029_Chapter2.pdf Restricted to Repository staff only Download (446kB)
	Text S_PSSF_A233029_Chapter3.pdf Restricted to Repository staff only Download (248kB)
	Text S_PSSF_A233029_Chapter4.pdf Restricted to Repository staff only Download (364kB)
	Text S_PSSF_A233029_Chapter5.pdf Restricted to Repository staff only Download (154kB)
	Text S_PSSF_A233029_Appendix.pdf Restricted to Repository staff only Download (936kB)

Abstract

Beta talasemia mayor merupakan kelainan genetik yang memerlukan transfusi darah rutin dan terapi khelasi besi untuk mencegah kelebihan zat besi. Khelasi besi sintetik yang ada memiliki efek samping dalam penggunaannya, sehingga diperlukan adjuvant sebagai pendukung. BRAZ 131 adalah produk herbal mengandung ekstrak kayu secang, kunyit dan lada putih berpotensi sebagai antioksidan dan pengkhelat besi. Penelitian ini bertujuan mengetahui pola konsumsi BRAZ 131 serta efek subjektif yang dirasakan penyandang talasemia. Penelitian menggunakan metode kualitatif deskriptif, dengan data primer, tidak melakukan intervensi, pengambilan data menggunakan kuesioner, pengambilan sampel dengan teknik purposive sampling dan waktu pelaksanaan secara cross-sectional pada periode Mei sampai Juli 2025. Hasil menunjukkan 52,2% responden mengonsumsi BRAZ 131 bersamaan dengan khelasi besi, 2 kali sehari 1 kapsul (43,5%), dan 78,3% rutin setiap hari. Efek positif yang dirasakan meliputi peningkatan nafsu makan (34,4%, badan lebih segar (28,1%) kulit lebih lembab (12,5%) dan kestabilan Hb 9,4%, penurunan feritin, jarang sakit, badan bertenaga dan semangat masing masing 3,1%. Efek negatif tidak ada (87%), kenaikan kadar feritin (8,7%), pusing (4,3%). Kesimpulan pada penelitian ini pola penggunaan BRAZ 131 digunakan kombinasi dengan khelasi besi, 2 kali sehari 1 kapsul dengan efek yang dirasakan paling banyak yaitu nafsu makan bertambah dan dominan tidak mengalami efek samping. ------- Beta thalassemia major is a genetic disorder that requires routine blood transfusions and iron chelation therapy to prevent iron overload. The existing synthetic iron chelation has side effects in its use, so an adjuvant is needed as a support. BRAZ 131 is an herbal product containing sappang wood extract, turmeric and white pepper with potential as antioxidants and iron chelator. This study aims to determine the consumption patterns of BRAZ 131 and the subjective effects felt by people with thalassaemia. The research used a descriptive qualitative method, with primary data, no intervention, data collection using questionnaires, sampling with purposive sampling techniques and the implementation time cross-sectional in the period from May to July 2025. The results showed that 52.2% of respondents took BRAZ 131 along with iron chelation, 1 capsule 2 times a day (43.5%), and 78.3% regularly daily. The positive effects felt included an increase in appetite (34.4%), a fresher body (28.1%), more moisturized skin (12.5%) and a 9.4% hemoglobin stability, a decrease in ferritin, less pain, a stronger body and a spirit of 3.1% each. Negative effects were absent (87%), increased ferritin levels (8.7%), dizziness (4.3%). The conclusion of this study is that the pattern of using BRAZ 131 is used in combination with iron chelation, 2 times a day 1 capsule with the most effects felt, namely increased appetite and dominantly do not experience side effects.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Adjuvant, BRAZ 131, efek subjektif, talasemia. ---- Adjuvant, BRAZ 131, subjective effect, thalassemia.
Subjects:	R Medicine > R Medicine (General) R Medicine > RA Public aspects of medicine
Divisions:	Program Studi S1 Farmasi
Depositing User:	pustakawan - -
Date Deposited:	10 Sep 2025 02:46
Last Modified:	10 Sep 2025 02:46
URI:	http://repository.stfi.ac.id/id/eprint/2786

Actions (login required)

View Item