UJI AKTIVITAS ANTIOKSIDAN EKSTRAK DAN FRAKSI HERBA RUMPUT MUTIARA (Oldenlandiae corymbose L.) DENGAN METODE Ferric Reducing Antioxidant Power (FRAP)

MUHAMMAD WITO QOMARUZAMAN, - (2025) UJI AKTIVITAS ANTIOKSIDAN EKSTRAK DAN FRAKSI HERBA RUMPUT MUTIARA (Oldenlandiae corymbose L.) DENGAN METODE Ferric Reducing Antioxidant Power (FRAP). Skripsi thesis, Sekolah Tinggi Farmasi Indonesia.

	Text S_PSSF_A211104_Title.pdf Download (413kB)
	Text S_PSSF_A211104_Chapter1.pdf Restricted to Repository staff only Download (252kB)
	Text S_PSSF_A211104_Chapter2.pdf Restricted to Repository staff only Download (381kB)
	Text S_PSSF_A211104_Chapter3.pdf Restricted to Repository staff only Download (346kB)
	Text S_PSSF_A211104_Chapter4.pdf Restricted to Repository staff only Download (384kB)
	Text S_PSSF_A211104_Chapter5.pdf Restricted to Repository staff only Download (248kB)
	Text S_PSSF_A211104_Appendix.pdf Restricted to Repository staff only Download (854kB)

Abstract

Radikal bebas merupakan molekul reaktif yang dapat menyebabkan kerusakan biomolekul tubuh, memicu stres oksidatif, dan berkontribusi terhadap berbagai penyakit degeneratif seperti kanker dan diabetes. Penggunaan antioksidan yang berasal dari alam saat ini banyak diteliti karena tanaman memiliki potensi sebagai antioksidan. Rumput mutiara (Oldenlandia corymbosa L.) dikenal mengandung senyawa fenolik, flavonoid, dan asam linoleat yang berpotensi sebagai antioksidan alami. Penelitian ini bertujuan untuk mengevaluasi aktivitas antioksidan ekstrak dan fraksi herba rumput mutiara menggunakan metode Ferric Reducing Antioxidant Power (FRAP). Ekstrak didapat menggunakan metode maserasi menggunakan etanol 97% dan difraksinasi dengan metode ekstraksi cair-cair. Hasil penelitian menunjukkan bahwa kapasitas antioksidan tertinggi ditunjukkan oleh fraksi etil asetat 1761,4004  243,9145 µmol TR/g, diikuti fraksi air 1590,2323  9,3099 µmol TR/g, fraksi n-heksan 1572,447  17,0602 µmol TR/g, dan ekstrak 1121,3371  55,087 µmol TR/g. Berdasarkan pengelompokan kapasitas antioksidan, seluruh sampel dikategorikan sebagai antioksidan kuat. Fraksi etil asetat memiliki potensi paling tinggi sebagai sumber antioksidan alami yang berpotensi dikembangkan lebih lanjut dalam pemanfaatan sebagai sumber antioksidan alami. ------ Free radicals are reactive molecules that can cause damage to the body's biomolecules, trigger oxidative stress, and contribute to various degenerative diseases such as cancer and diabetes. The use of natural antioxidants is currently being widely researched because plants have the potential to act as antioxidants. Pearl grass (Oldenlandia corymbosa L.) is known to contain phenolic compounds, flavonoids, and linoleic acid, which have potential as natural antioxidants. This study aims to evaluate the antioxidant activity of pearl grass herb extracts and fractions using the Ferric Reducing Antioxidant Power (FRAP) method. The extracts were obtained using the maceration method with 97% ethanol and fractionated using the liquid-liquid extraction method. The results showed that the highest antioxidant capacity was exhibited by the ethyl acetate fraction 1761,4004  243,9145 µmol TR/g, followed by the water fraction 1590,2323  9,3099µmol TR/g, n-hexane fraction 1572,447  17,0602µmol TR/g, and the whole extract 1121,3371  55,087 µmol TR/g. Based on the antioxidant capacity classification, all samples were categorized as strong antioxidants. The ethyl acetate fraction has the highest potential as a natural antioxidant source that could be further developed for use as a natural antioxidant source.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Rumput mutiara, antioksidan, FRAP, TEAC. ------- Pearl grass, antioxidants, FRAP, TEAC
Subjects:	Q Science > Q Science (General) Q Science > QH Natural history > QH301 Biology
Divisions:	Program Studi S1 Farmasi
Depositing User:	pustakawan - -
Date Deposited:	03 Sep 2025 02:26
Last Modified:	03 Sep 2025 02:26
URI:	http://repository.stfi.ac.id/id/eprint/2752

Actions (login required)

View Item