MARKUS GULTOM, - (2025) PENGARUH METODE AEROPONIK DAN PENAMBAHAN BENZIL AMINO PURIN TERHADAP KADAR SENYAWA ANDROGRAFOLID PADA TANAMAN SAMBILOTO (Andrographis Paniculata Ness). Skripsi thesis, Sekolah Tinggi Farmasi Indonesia.
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Abstract
Sambiloto (Andrographis paniculata Ness) merupakan tanaman obat yang mengandung senyawa bioaktif utama andrografolid, yang memiliki berbagai aktivitas farmakologis, termasuk sebagai antidiabetes. Kandungan andrografolid dalam tanaman sangat dipengaruhi oleh teknik budidaya dan ketersediaan zat pengatur tumbuh (ZPT). Penerapan metode aeroponik dengan penambahan Benzil Amino Purin (BAP) berpotensi mengoptimalkan pertumbuhan tanaman dan meningkatkan akumulasi metabolit sekunder. Penelitian ini bertujuan untuk mengevaluasi pengaruh variasi konsentrasi BAP terhadap parameter pertumbuhan dan kadar andrografolid pada tanaman sambiloto. Bibit sambiloto berumur satu bulan dibudidayakan menggunakan sistem aeroponik dengan larutan nutrisi AB Mix yang diformulasikan melalui perangkat lunak HydroBuddy, disertai perlakuan tiga konsentrasi BAP (1 ppm, 2 ppm, dan 5 ppm) serta kontrol tanpa penambahan BAP. Parameter morfologi yang diamati meliputi panjang batang, jumlah daun, dan panjang akar selama 16 hari masa perlakuan. Analisis kadar andrografolid pada daun dan batang dilakukan secara kuantitatif menggunakan High Performance Liquid Chromatography (HPLC). Hasil penelitian menunjukkan bahwa perlakuan BAP 2 ppm memberikan respon pertumbuhan terbaik, dengan panjang batang 24 cm, jumlah daun 23 helai, panjang akar 7 cm, serta kadar andrografolid tertinggi pada daun sebesar 0,863%, dibandingkan kontrol sebesar 0,378%. Dengan demikian, metode aeroponik dengan penambahan BAP 2 ppm terbukti efektif dalam meningkatkan pertumbuhan dan kandungan andrografolid tanaman sambiloto, sehingga berpotensi diterapkan sebagai strategi budidaya untuk mendukung produksi fitofarmaka berkualitas tinggi. ------- Sambiloto (Andrographis paniculata Ness) is a medicinal plant containing andrographolide as its main bioactive compound, known for various pharmacological activities, including antidiabetic properties. The andrographolide content in the plant is strongly influenced by cultivation techniques and the availability of plant growth regulators. The application of the aeroponic method with the addition of Benzyl Amino Purine (BAP) has the potential to optimize plant growth and enhance the accumulation of secondary metabolites. This study aimed to evaluate the effect of different BAP concentrations on the growth parameters and andrographolide content of A. paniculata. One-month-old seedlings were cultivated in an aeroponic system using AB Mix nutrient solution formulated with HydroBuddy software, with treatments consisting of three BAP concentrations (1 ppm, 2 ppm, and 5 ppm) and a control without BAP. Morphological parameters observed included stem length, leaf number, and root length over a 16-day treatment period. Andrographolide content in leaves and stems was quantitatively analyzed using High Performance Liquid Chromatography (HPLC). The results showed that 2 ppm BAP treatment yielded the best growth response, with a stem length of 24 cm, 23 leaves, root length of 7 cm, and the highest andrographolide content in leaves (0.863%), compared to the control (0.378%). In conclusion, the aeroponic method with 2 ppm BAP effectively enhanced both growth and andrographolide content in A. paniculata, and could serve as a viable cultivation strategy for producing highquality phytopharmaceuticals.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | Andrographis paniculata, aeroponik, BAP, andrografolid, HPLC. ------ Andrographis paniculata, aeroponics, BAP, andrographolide, HPLC |
| Subjects: | Q Science > Q Science (General) Q Science > QD Chemistry |
| Divisions: | Program Studi S1 Farmasi |
| Depositing User: | pustakawan - - |
| Date Deposited: | 01 Sep 2025 03:22 |
| Last Modified: | 01 Sep 2025 03:22 |
| URI: | http://repository.stfi.ac.id/id/eprint/2745 |
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