EFEK FARMAKOLOGI DAN ANALISIS SENYAWA DARI KRATOM (Mitragyna speciosa Korth) SEBAGAI PENGOBATAN BARU

MUHAMMAD TAUFIQ, - (2020) EFEK FARMAKOLOGI DAN ANALISIS SENYAWA DARI KRATOM (Mitragyna speciosa Korth) SEBAGAI PENGOBATAN BARU. Skripsi thesis, Sekolah Tinggi Farmasi Indonesia.

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Abstract

Pohon Mitragyna speciosa Korth. (Rubiaceae) ditemukan di Asia Tenggara (Thailand, Indonesia, Malaysia, Myanmar, Filipina dan Papua Nugini). Secara tradisional, Mitragyna speciosa digunakan untuk meredakan nyeri, hipertensi, batuk, diare dan sebagai pengganti morfin untuk mengobati pecandu. Association of Southeast Asian Nations (ASEAN), menyebut kratom sebagai obat. Kratom mengandung lebih dari 40 jenis alkaloid diantaranya mitraginin sebanyak (66,2%) dan turunannya, speciogynine (6,6%), speciociliatine (0,8%), paynantheine (8,6%), 7-hidroksimitraginin (2%). Artikel ini dibuat untuk memberikan informasi terkait efek farmakologis kratom, analisis senyawa kratom, dan potensi senyawa dari kratom menjadi obat baru. Metode yang digunakan dalam penelitian ini adalah review dan menganalisis artikel kratom dari makalah penelitian, review bibliografi dan laporan kasus termasuk, penelitian yang dilakukan di Indonesia dan dalam bahasa Inggris. Dari hasil review yang di dapat penggunaan kratom (Mitragyna speciosa Korth.) sebagai bahan baku obat dalam dunia kesehatan dianjurkan menggunakan senyawa mitraginin yang dosisnya dapat diatur dengan mudah tergantung tujuan penggunaan dan efek farmakologis yang diinginkan. --- Mitragyna speciosa Korth. (Rubiaceae) a tree found in Southeast Asia (Thailand, Indonesia, Malaysia, Myanmar, Philippines and Papua New Guinea. Traditionally, the Mitragyna speciosa was used to alleviate pain, hypertension, cough, diarrhea and as a substitute for morphine in treating addicts. Association of Southeast Asian Nations, refers to kratom as a drug. Kratom contains more than 40 types of alkaloids including Mitraginin, as many as (66.2%) and their derivatives, speciogynine (6.6%), speciociliatine (0.8%), paynantheine (8.6%), 7- hidroksi Mitraginin (2%). The article was created to provide information related to the pharmacological effects of kratom, kratom compound analysis, and the potential of compounds from kratom to become new drugs. The method used in this research is to review and analyze kratom articles from research papers, bibliographic reviews and case reports included, research conducted in Indonesia and in English. The main purpose of this review is not only to understand the chemical content, benefits of kratom, and analytical methodologies for analysis, but also the use of kratom secondary metabolites as therapeutic drugs and the side effects associated with their consumption, to help health professionals assess the content of compounds from kratom worthy of being new drugs.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Kratom, Mitragyna speciosa Korth, efek farmakologi, laporan kasus, toksisitas, manfaat, obat baru. --- Kratom, Mitragyna speciosa Korth; effect pharmacology; case report; toxicity; benefits; new drugs.
Subjects:	Q Science > Q Science (General) R Medicine > R Medicine (General)
Divisions:	Program Studi S1 Farmasi
Depositing User:	pustakawan - -
Date Deposited:	03 Oct 2024 06:28
Last Modified:	03 Oct 2024 06:28
URI:	http://repository.stfi.ac.id/id/eprint/1325

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