SIDIK PERFUSI MIOKARD SEDIAAN RADIOFARMASI TEKNESIUM-METOKSI-ISOBUTIL-ISONITRIL (99MTc-MIBI) PADA PASIEN DIABETES MELLITUS

FAZAR HAMZYAH, - (2020) SIDIK PERFUSI MIOKARD SEDIAAN RADIOFARMASI TEKNESIUM-METOKSI-ISOBUTIL-ISONITRIL (99MTc-MIBI) PADA PASIEN DIABETES MELLITUS. Skripsi thesis, Sekolah Tinggi Farmasi Indonesia.

	Text S_PSSF_A162010_Title.pdf Download (684kB)
	Text S_PSSF_A162010_Chapter1.pdf Restricted to Repository staff only Download (131kB)
	Text S_PSSF_A162010_Chapter2.pdf Restricted to Repository staff only Download (238kB)
	Text S_PSSF_A162010_Chapter3.pdf Restricted to Repository staff only Download (16kB)
	Text S_PSSF_A162010_Chapter4.pdf Restricted to Repository staff only Download (185kB)
	Text S_PSSF_A162010_Chapter5.pdf Restricted to Repository staff only Download (5kB)
	Text S_PSSF_A162010_Appendix.pdf Restricted to Repository staff only Download (169kB)

Abstract

Salah satu komplikasi penyakit Diabetes Mellitus (DM) yang paling berbahaya dan banyak menyebabkan kematian adalah penyakit jantung coroner (PJK), yaitu terjadinya sumbatan/berkurangnya suplai darah ke jantung yang sulit terduga (silent killer). Beberapa metode diagnosis untuk deteksi dini PJK masih terus dikembangkan. Dalam penelitian ini telah dilakukan studi retrospektif untuk membandingkan Sidik Perfusi Miokard menggunakan sediaan radiofarmasi 99mTc-MIBI dengan sidik EKG terhadap 12 pasien terduga DM tipe-2. Dari 12 pasien terduga DM yang melakukan EKG, diperoleh data 10 pasien dinyatakan tidak menunjukkan kelainan PJK, 1 pasien terindikasi defek/kelainan, dan 1 pasien dinyatakan meragukan, sedangkan pada hasil Sidik Perfusi Miokard diperoleh data 2 pasien normal, 10 pasien menunjukkan defek/kelainan, dan tidak ada satu pun hasil yang meragukan. Dari hasil evaluasi data terlihat bahwa Sidik Perfusi Miokard 99mTc-MIBI memberikan prospek lebih baik dan dapat direkomendasikan sebagai metode uji tapis (screening test) penyakit jantung koroner (PJK), dan bahkan diharapkan dapat dijadikan metode pilihan bagi para dokter untuk mengungkap berbagai kasus PJK lebih dini, khususnya pada kasus DM. --- One of the complications of Diabetes Mellitus (DM) that is the most dangerous and causes many deaths is coronary artery disease (CAD), which is the occurrence of blockage / reduced blood supply to the heart which is unpredictable (silent killer). Several diagnostic methods for early detection of CAD are still being developed. In this study, a retrospective study was conducted to compare the myocardial perfusion scan using a 99mTc-MIBI radiopharmaceutical preparation with ECG fingerprints on 12 patients suspected of type-2 diabetes mellitus. Of the 12 suspected DM patients who performed an EKG, data were obtained from 10 patients who did not show CHD abnormalities, 1 patient indicated a defect / abnormality, and 1 patient was declared doubtful, while the results of the Myocardial Perfusion Scan showed 2 normal patients, 10 patients showed defects / abnormalities. , and not a single dubious result. From the results of the data evaluation, it can be seen that the 99mTc-MIBI Myocardial Perfusion Scan provides a better prospect and can be recommended as a screening test method for coronary artery disease (CAD), and is even expected to be the method of choice for doctors to reveal more cases of CAD. early, especially in the case of DM.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Studi Retrospektif, Diabetes Mellitus, 99mTc-MIBI, Sidik Perfusi Miokard, Penyakit Jantung Koroner (PJK). --- Retrospective Study, Diabetes Mellitus, 99mTc-MIBI, Myocardial Perfusion Scan, Coronary Artery Disease (CAD)
Subjects:	Q Science > Q Science (General) R Medicine > R Medicine (General)
Divisions:	Program Studi S1 Farmasi
Depositing User:	pustakawan - -
Date Deposited:	02 Oct 2024 04:33
Last Modified:	02 Oct 2024 04:33
URI:	http://repository.stfi.ac.id/id/eprint/1289

Actions (login required)

View Item