ELISABET NANDA KRISTIN, - (2022) PENETAPAN KADAR LARUT ISOLAT METIL SINAMAT DALAM PELARUT AKUADES, ASAM, BASA, DAN ETIL ASETAT MENGGUNAKAN METODE SPEKTROFOTOMETRI ULTRAVIOLET. Skripsi thesis, Sekolah Tinggi Farmasi Indonesia.
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Abstract
Metil sinamat merupakan senyawa ester dari asam sinamat yang mempunyai rumus kimia C10H10O2, mempunyai bentuk kristal berwarna putih hingga kekuningan. Dalam bidang kesehatan, metil sinamat biasanya digunakan sebagai antelmintik dan memiliki aktivitas sebagai tabir surya. Saat ini data kelarutan metil sinamat belum banyak diketahui, sehingga penelitian ini bertujuan untuk menguji kelarutan metil sinamat dalam pelarut akuades, asam pH 1,5, basa pH 8,0, dan etil asetat menggunakan metode spektrofotometri ultraviolet. Hasil penelitian kelarutan metil sinamat yang telah dilakukan menggunakan metode spektrofotometri ultraviolet menunjukkan kelarutan metil sinamat dalam pelarut akuades sebesar 0,0005 g/mL dengan perbandingan kelarutan 1:2.000, pelarut asam sebesar 0,0003 g/mL dengan perbandingan kelarutan 1:3.333, pelarut basa sebesar 0,0005 g/mL dengan perbandingan kelarutan 1:2.000, dan dalam pelarut etil asetat sebesar 3,7733 g/mL dengan nilai perbandingan 1:0,2650. Berdasarkan penelitian yang telah dilakukan, dapat disimpulkan bahwa metil sinamat bersifat sukar larut dalam pelarut akuades, asam, dan basa serta bersifat sangat mudah larut dalam pelarut etil asetat. --- Methyl cinnamate is an ester compound of cinnamic acid which has the chemical formula C10H10O2, has a white to yellowish crystalline form. In the health sector, methyl cinnamate is usually used as an anthelmintic and has activity as a sunscreen. Currently, data on the solubility of methyl cinnamate is not widely known, so this study aimed to test the solubility of methyl cinnamate in aquadest, acid pH 1,5, base pH 8,0, and ethyl acetate using ultraviolet spectrophotometric method. The results of the solubility research of methyl cinnamate that have been carried out using the ultraviolet spectrophotometric method showed the solubility of methyl cinnamate in distilled water was 0,0005 g/mL with a solubility ratio of 1:2.000, acid solvent was 0,0003 g/mL with a solubility ratio of 1: 3.333, solvent base was 0,0005 g/mL with a solubility ratio of 1:2.000, and in ethyl acetate solvent was 3,7733 g/mL with a ratio value of 1:0,2650. Based on the research that has been done, it can be concluded that methyl cinnamate is difficult to dissolve in aquadest, acids, and bases and is very soluble in ethyl acetate solvent.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | metil sinamat, kelarutan, spektrofotometri ultraviolet. --- methyl cinnamate, solubility, spectrophotometric ultraviolet. |
| Subjects: | Q Science > Q Science (General) |
| Divisions: | Program Studi S1 Farmasi |
| Depositing User: | pustakawan - - |
| Date Deposited: | 14 Sep 2024 15:35 |
| Last Modified: | 14 Sep 2024 15:35 |
| URI: | http://repository.stfi.ac.id/id/eprint/1217 |
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