UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN KITOLOD (Isotoma longiflora L.) TERHADAP PERTUMBUHAN BAKTERI Streptococcus pneumoniae

ICA FITRIAH, - (2022) UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN KITOLOD (Isotoma longiflora L.) TERHADAP PERTUMBUHAN BAKTERI Streptococcus pneumoniae. Skripsi thesis, Sekolah Tinggi Farmasi Indonesia.

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Abstract

Kitolod (Isotoma longiflora L.) merupakan tanaman liar yang biasa dimanfaatkan sebagai tanaman obat. Penelitian ini bertujuan untuk menguji aktivitas antibakteri ekstrak daun kitolod terhadap pertumbuhan bakteri Streptococcus pneumoniae dan untuk mengetahui pada konsentrasi berapa ekstrak daun kitolod menghambat pertumbuhan bakteri Streptococcus pneumoniae. Pada penapisan fitokimia memberikan hasil bahwa daun kitolod memiliki kandungan metabolit sekunder yaitu fenol, flavonoiod, steroid dan triterpenoid. Pengujian aktivitas antibakteri dilakukan dengan menggunakan metode Kirby-Bauer (metode cakram). Pengujian dilakukan dengan beberapa variasi konsentrasi yang digunakan yaitu 40%, 20%, 10% dan 5%. Pengenceran ekstrak daun kitolod menggunakan campuran pelarut akuades steril dan DMSO, sebagai pembanding digunakan amoksisilin trihidrat. Pada konsentrasi 40% menunjukkan diameter zona hambat pada Streptococcus pnemoniae sebesar 2 mm, konsentrasi 20% sebesar 0,7 mm, konsentrasi 10% sebesar 0,7 mm, konsentrasi 5% sebesar 0,7 mm dan pada pembanding menggunakan amoksisilin didapatkan hasil diameter zona hambat sebesar 3,1 mm. Berdasarkan hasil penelitian dapat disimpulkan bahwa ekstrak daun kitolod memiliki aktivitas antibakteri yang lemah terhadap bakteri Streptococcus pneumoniae. --- Kitolod (Isotoma longiflora L.) is a wild plant that is commonly used as a medicinal plant. This study aimed to test the antibacterial activity of kitolod leaf extract against the growth of Streptococcus pneumoniae bacteria and to determine at what concentration the kitolod leaf extract inhibited the growth of Streptococcus pneumoniae bacteria. The phytochemical screening showed that kitolod leaves contain secondary metabolites, namely phenols, flavonoids, steroids and triterpenoids. Antibacterial activity testing was carried out using the Kirby-Bauer method (disc method). The test was carried out with several variations of the concentration used, namely 40%, 20%, 10% and 5%. Kitolod leaf extract was diluted using a mixture of sterile distilled water and DMSO, while amoxicillin trihydrate was used as a comparison. At a concentration of 40%, the diameter of the inhibition zone on Streptococcus pneumoniae was 2 mm, the concentration of 20% was 0.7 mm, the concentration of 10% was 0.7 mm, the concentration of 5% was 0.7 mm and in comparison using amoxicillin, the results showed that the diameter of the zone was 0.7 mm. resistance of 3.1 mm. Based on the results of the study, it can be concluded that kitolod leaf extract has weak antibacterial activity against Streptococcus pneumoniae bacteria.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Kitolod, Antibakteri, Streptococcus pneumoniae --- Kitolod, Antibacterial, Streptococcus pneumoniae
Subjects:	Q Science > Q Science (General) Q Science > QH Natural history > QH301 Biology
Divisions:	Program Studi S1 Farmasi
Depositing User:	pustakawan - -
Date Deposited:	14 Sep 2024 04:29
Last Modified:	14 Sep 2024 04:29
URI:	http://repository.stfi.ac.id/id/eprint/1179

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