REVIEW: AKTIVITAS FARMAKOLOGI DAN SENYAWA KIMIA DARI GENUS PERSEA

SHELI MELIANA SURYATI, - (2021) REVIEW: AKTIVITAS FARMAKOLOGI DAN SENYAWA KIMIA DARI GENUS PERSEA. Skripsi thesis, Sekolah Tinggi Farmasi Indonesia.

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Abstract

Jenis Persea tersebar luas di berbagai daerah bahkan sampai di berbagai negara. Persea merupakan salah satu genus yang memiliki aktivitas farmakologi yang beragam. Ulasan ini mencakup tinjauan jenis dari Persea, senyawa kimia dari hasil isolasi, dan aktivitas farmakologinya dengan pencarian secara online dari beberapa publikasi ilmiah baik nasional maupun internasional. Aktivitas farmakologi Persea terbanyak adalah aktivitas antibakteri. Senyawa kimia yang telah diisolasi dari genus Persea masuk ke dalam golongan flavonoid, terpenoid, asam lemak, hidrokarbon, sterol dan lignan. Turunan kuersetin dari golongan flavonoid merupakan senyawa paling banyak dilaporkan. Jenis Persea yang paling banyak dilaporkan yaitu dari jenis Persea americana. Menurut data The Plant List spesies dari genus Persea yang dilaporkan berjumlah 429 spesies, tetapi untyk data spesies yang sudah diterima berjumlah 99 spesies. Data dari hasil literatur menunjukkan bahwa hanya 9 spesies dari genus Persea yang telah dilaporkan memiliki aktivitas farmakologi dan senyawa kimia hasil isolasi. Berdasarkan hal ini banyak jenis Persea lainnya yang berpotensi dijadikan sebagai bahan baku penelitian khususnya spesies yang sudah dilaporkan. Maka dari itu, diperlukan penelitian lanjutan studi pustaka mengenai aktivitas farmakologi dan senyawa kimia, khususnya selain antibakteri dan antioksidan dari genus Persea yang sudah dilaporkan. --- Persea species are widespread in various regions and even in various countries. Persea is a gems that has diverse pharmacological activities. This review includes an overview of the species of Persea, the chemical compounds isolated, and their pharmacological activities by searching online from several national and international scientific publications. The most pharmacological activity of Persea is antibacterial activity. Chemical compounds that have been isolated from the genus Persea belong to the group of flavonoids, terpenoids, fatty acids, hydrocarbons, sterols and lignans. Quercetin derivatives from the flavonoid group were the most widely reported compounds. The most widely reported species of Persea is from the type Persea americana. According to data from The Plant List, the reported species of the gema Persea are 429 species, but for species data that have been received, there are 99 species. Data from the literature show that only 9 species of the genus Persea have been reported to have pharmacological activity and isolated chemical compounds. Based on this, many other Persea species have the potential to be used as research raw materials, expecially the species that have been reported. Therefore, further research is needed to study literature on pharmacological activities and chemical compounds, especially in addition to antibacterial and antioxidant from the genus Persea that have been reported.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Genus Persea, Aktivitas farmakologi, Antibakteri, Kuersetin --- Persea genus, Pharmacological activities, Antibacterial, Quercetin
Subjects:	Q Science > Q Science (General) R Medicine > RM Therapeutics. Pharmacology
Divisions:	Program Studi S1 Farmasi
Depositing User:	pustakawan - -
Date Deposited:	07 Sep 2024 01:35
Last Modified:	07 Sep 2024 01:35
URI:	http://repository.stfi.ac.id/id/eprint/1161

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