FORMULASI DAN UJI ANTIMIKROBA GEL HAND SANITIZER YANG MENGANDUNG MINYAK ATSIRI HERBA KEMANGI (Ocimum americanum L.)

ELFANI DAMAYANTI, - (2021) FORMULASI DAN UJI ANTIMIKROBA GEL HAND SANITIZER YANG MENGANDUNG MINYAK ATSIRI HERBA KEMANGI (Ocimum americanum L.). Skripsi thesis, Sekolah Tinggi Farmasi Indonesia.

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Abstract

Kemangi merupakan tumbuhan yang mudah dijumpai serta memiliki banyak manfaat. Kemangi juga diketahui memiliki kandungan minyak atsiri yang dapat digunakan sebagai antimikroba, sehingga dapat dimanfaatkan sebagai antiseptik herbal. Tujuan dari penelitian ini adalah untuk menguji minyak atsiri kemangi dapat diformulasikan menjadi sediaan gel hand sanitizer yang memiliki aktivitas antimikroba melalui pengujian menggunakan metode difusi. Minyak atsiri kemangi diformulasikan menjadi sediaan gel menggunakan gelling agent Carbopol 990. Kadar minyak atsiri kemangi yang diuji aktivitas antibakterinya adalah 5%, 7,5% dan 10%, dari ketiga kadar tersebut kadar 7,5% yang digunakan untuk formulasi sediaan gel hand sanitizer. Hasil penelitian menunjukkan bahwa minyak atsiri kemangi dapat diformulasikan menjadi sediaan gel hand sanitizer yang memenuhi persyaratan; uji organoleptis, pH, viskositas, daya sebar, dan sentrifugasi. Hasil uji aktivitas antimikroba terhadap bakteri Escherichia coli menunjukkan zona hambat sebesar 6,6 mm dan pada Staphylococcus aureus sebesar 4,6 mm. Kesimpulan dari penelitian ini minyak atsiri kemangi dapat diformulasikan menjadi sediaan gel hand sanitizer yang memiliki aktivitas antimikroba. --- Basil is a plant that is easy to find and has many benefits. Basil is also known to contain essential oils that can be used as antimicrobials, so they can be used as herbal antiseptics. The purpose of this study was to test that basil essential oil can be formulated into a hand sanitizer gel preparation that has antimicrobial activity through testing using the diffusion method. Basil essential oil was formulated into gel preparations using the gelling agent Carbopol 990. The concentration of basil essential oil tested for antibacterial activity were 5%, 7.5% and 10%, of the three levels, 7.596 was used for the formulation of hand sanitizer gel preparations. sanitizers. The results showed that basil essential oil can be formulated into hand sanitizer gel preparations that meet the requirements; organoleptic test, pH, viscosity, spreadability, and centrifugation. The results of the antimicrobial activity test against Escherichia coli showed an inhibition zone of 6.6 mm and Staphylococcus aureus 4.6 mm. The conclusion of this study is that basil essential oil can be formulated into a hand sanitizer gel preparation that has antimicrobial activity.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Minyak atsiri kemangi, gei hand sanitizer, antibakteri --- Basil essential oil, hand sanitizer gel, antibacterial
Subjects:	Q Science > Q Science (General) R Medicine > R Medicine (General)
Divisions:	Program Studi S1 Farmasi
Depositing User:	pustakawan - -
Date Deposited:	07 Sep 2024 02:02
Last Modified:	07 Sep 2024 02:02
URI:	http://repository.stfi.ac.id/id/eprint/1145

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